synovial fluid inflammatory cytokines and proteins in clinically healthy and arthritic joint of dromedary camels (camelus dromedarius)

Authors

mohammad hasan najizadeh

mehrdad pourjafar

ali asghar chalmeh

khalil badiei

saeed nazifi

abstract

analyzing the synovial fluid is one of the common methods to diagnose the articular problems to detect the stage and express the prognosis. such gross, cytological, and biochemical analysis of synovial fluids can aid in the diagnosis of various joint diseases. objectives: normal values for synovial fluid in the camels have been described previously; however, there are no reports regarding concentr-ation of acute phase proteins and inflammatory cytokines in camelids synovial fluid. hence, the present study tried to compare the synovial fluid inflammatory cytokines and acute phase proteins in clinically healthy and arthritic tarsal joints of dromedary camels. methods: 46 male dromedary camels, 5 to 10 years old, were used in this study. 33 camels did not have any clinical articular abnormalities while 13 camels had gross articular problems such as lameness and swollen tarsal joints. collecting the synovial fluids was extracted from the healthy and arthritic tarsal joints immediately after slaughter. then, the concentration of haptoglobin, serum amyloid a, tumor necrosis factor-alpha, and interferon-gamma were measured in samples. results: concentration of all measured parameters in arthritic joints were significantly higher than clinically healthy joints (p

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Journal title:
iranian journal of veterinary medicine

Publisher: دانشگاه تهران

ISSN 2251-8894

volume 8

issue 1 2014

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